How Obesity Can Rewire the Immune System and the Response to Immunotherapy

Gladstone Insitutes / March 30, 2022 / When mice with atopic dermatitis—a common type of allergic skin inflammation—are treated with drugs that target the immune system, their thickened, itchy skin generally heals quickly. But scientists have now discovered that the same treatment in obese mice makes their skin worse instead. That is because obesity changes the molecular underpinnings of allergic inflammation, both in mice and humans.Read more at gladstone.org.